Chinesename:Cetrelixacetate
Englishname:Cetrorelixacetate
CASnumber:120287-85-6
Molecularformula:C70H92ClN17O14
Molecularweight:1431.04
Meltingpoint:>259°C(dec.)
Density:1.42±0.1g/cm3(Predicted)
Storagecondition:Refrigerator
Solubility:DMSO(Slightly,Heated),Methanol(VerySlightly)
Form:Solid
Aciditycoefficient(kPa):9.82±0.15(Predicted)
Color:WhitetoOff-White
Application:Cetrelixacetateisasyntheticdecapeptide,whichismainlyusedinassistedreproductivetechnologytopreventprematureovulationinpatientswithcontrolledovarianstimulation.Rickisagonadotropin-releasinghormone(GnRH)antagonistthatcancompetewithendogenousLHRHtobindtoreceptorsonthepituitarycellmembrane,therebyinhibitingthesecretionofluteinizinghormone(LH)andfolliclestimulatinghormone(FSH)bythepituitarydose-dependent.